Cardiovascular protective effects of astragaloside IV
نویسندگان
چکیده
منابع مشابه
Protective Effects of Astragaloside IV on db/db Mice with Diabetic Retinopathy
OBJECTIVES Diabetic retinopathy (DR) is a common diabetic eye disease which is well-known as the result of microvascular retinal changes. Although the potential biological functions of astragaloside IV (AS IV) have long been described in traditional system of medicine, its protective effect on DR remains unclear. This study aims to investigate the function and mechanism of AS IV on type 2 diabe...
متن کاملPharmacological effects of Astragaloside IV: a literature review.
OBJECTIVE To review the pharmacological effects and mechanisms of action of Astragaloside IV in Huangqi (Radix Astragali Mongolici). METHODS Aticles focusing on Astragaloside IV in English and Chinese in databases were collected and reviewed in order to summarize the latest extraction separation, pharmacokinetics, and the pharmacological effects of astrageloside IV. RESULTS Protective effec...
متن کاملEffects of Astragaloside IV on heart failure in rats
BACKGROUND Astragaloside IV (ASI) in Radix Astragali is believed to be the active component in treating heart failure. The present study aims to examine the effects of ASI on cardiovascular parameters in long-term heart failure in rats. METHODS Using echocardiographic and haemodynamic measurements, we studied the effects of ASI on congestive heart failure (CHF) induced by ligation of the left...
متن کاملAnti-fibrotic effects of Astragaloside IV in systemic sclerosis.
OBJECTIVE To evaluate the anti-fibrotic effects of Astragaloside IV in systemic sclerosis. METHODS Treated or untreated systemic sclerosis (SSc) and normal fibroblast isolated from corresponding pairs were utilized to detect expression of collagen and fibronectin by western blot, quantitative real-time RT-PCR (RT-qPCR), immunofluorescence staining and histopathological examination. SSc mouse ...
متن کاملEffects of Astragaloside IV on diabetic nephropathy in rats.
The aims of this study were to explore the effects of Astragaloside IV on diabetic nephropathy (DN) rats. A total of 38 male Sprague-Dawley (SD) rats were divided into three groups: 10 in the normal (control) group, 14 in the DN model group, and 14 in the AS-IV group. Treatment began one week after the streptozotocin DN model was successfully established. Blood glucose and urine micro-albumin l...
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ژورنال
عنوان ژورنال: Journal of Chinese Pharmaceutical Sciences
سال: 2013
ISSN: 1003-1057
DOI: 10.5246/jcps.2013.03.031